Adenomatoid odontogenic tumor aot is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. Salient features of adenomatoid odontogenic tumor and. The 3 variants follicular, extrafollicular and peripheral present with identical histological. We present a case of aot in a 14yearold male who was misdiagnosed as. Adenomatoid odontogenic tumor involving maxillary sinus. Int j oral maxillofac surg decade of life, the first in a girl and the figure 1. However, adenomatoid odontogenic tumor occurs mostly in the anterior maxillary region and is associated in 60% of cases with a canine 3, 10, 14, 15. Selected issues that were studied included the following. Odontogenic and non odontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance. The adenomatoid odontogenic tumour aot has been known by a number of descriptive names adenoameloblastoma, ameloblastic adenomatoid tumour, glandular ameloblastoma, and adenomatoid. It is a benign hamartomatous, noninvasive lesion with slow but progressive growth. Abstract adenomatoid odontogenic tumour aot, a tumour composed of odontogenic epithelium, is an uncommon tumour of odontogenic origin that accounts for only 2.
It is a relatively uncommon neoplasm that accounts for about 3% of all odontogenic tumors being more common in the maxilla and in females, more often associated with impacted canines 1 2 3. Aot accounts for about 1% until 9% of all odontogenic tumors. Molecular profiling of odontogenic tumors pilot study in. Adenomatoid definition of adenomatoid by medical dictionary. Ahire ms, tupkari jv, chettiankandy tj, thakur a, agrawal rr. It appears mostly in young patients and females, the maxillary. Clinically these are similar to gingival fibrous lesions and cannot be differentiated from. An adenomatoid odontogenic tumor aot is a rare, benign epithelial odontogenic tumor which accounts for 27% of all odontogenic tumors. Adenomatoid odontogenic tumor aot is a wellrecognised slow growing benign tumor derived from complex system of dental lamina or its remnants. Adenomatoid tumors of the scrotum are benign, solid extratesticular lesions that can originate from the epididymis, tunica vaginalis, or spermatic cord 90% derived from the funiculus. The who histological typing of odontogenic tumors, jaw cyst and allied lesions 2005 has defined aot as a tumor of odontogenic epithelium with ductlike. Adenomatoid odontogenic tumour aot is a benign noninvasive odontogenic tumour, having mostly a slow and sustained growth pattern. The adenomatoid odontogenic tumor aot is usually an asymptomatic slow growth lesion. A, e multiple epithelial follicles with calcifications arrows.
Adenomatoid odontogenic tumors are rare and differ from most other dentition related lesions in that they more frequently occur in the maxilla epidemiology. It is predominantly found in young and female patients. In the whoiarc classification of head and neck pathology, this clinical entity had been known for years as the odontogenic keratocyst. Cases involving multiple regions or an entire quadrant are indicated between arrows.
An atypical adenomatoid odontogenic tumour in the mandible. Epidemiology they are the most common extratesticular neop. In the literature, it has been considered as a hamartoma rather. It is common for the tumor to cause shifting of neighboring teeth because tumor expansion is more common than teeth root resorption. Adenomatoid odontogenic tumor variants do not show distinctive clinical. Adenomatoid odontogenic tumor aot is an uncommon benign epithelial lesion of odontogenic origin and, thus far, only few studies regarding the frequency of its many histopathologic features have been published in the literature. Adenomatoid odontogenic tumor aot is a rare odontogenic tumour oontogenic is frequently misdiagnosed as odontogenic cyst. Adenomatoid odontogenic tumor pdf adenomatoid odontogenic tumor aot, a benign hamartomatous lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor oral and maxillofacial surgery. Although they do not normally contain odontogenic tissue, they are probably odontogenic because of their site of origin. Topographical distribution of the known precise locations n 646 of follicular adenomatoid odontogenic tumors aots. The adenomatoid odontogenic tumor aot is included in classifications of odontogenic tumors because it occurs only in the toothbearing area of the jaws and. All ameloblastomatic tumors were shown braf mutation and adenomatoid odontogenic tumors were kras mutation.
Very few cases of aot associated with dentigerous cyst dc have been reported till date, most cases are in females and have a striking tendency to. The aim of this update was to present the recent notable progress within remaining questions relating to the adenomatoid odontogenic tumour aot. A well circumscribed lesion derived from odontogenic epithelium that usually occurs around the crowns of unerupted anterior teeth of young patients and consists of epithelium in swirls and ductal patterns interspersed with spherical calcifications. This epithelial tumor has an inductive effect on the odontogenic ectomesenchyme with dentinoid frequently being produced. Pdf adenomatoid odontogenic tumor is an uncommon benign hamartomatous lesion of odontogenic origin, commonly seen in adolescents.
Adenomatoid odontogenic tumour aot is an uncommon, benign tumour that represents 37% of all odontogenic tumours. Pdf adenomatoid odontogenic tumor aot is a epithelial tumor with an inductive effect of odontogenic ectomesenchyme. Chapter 21 odontogenic and non odontogenic tumors of the jaws introduction. Adenomatoid odontogenic tumor aot formerly called an adenoameloblastoma, a somewhat deceptive term that should be discarded, the aot represents about 37 % of all odontogenic tumors. This evidence may highlight the poorly understood pathogenesis of odontogenic tumors. Sixtynine percent of adenomatoid odontogenic tumours are diagnosed in the second decade of life, and more than half occur during the. This report describes a patient with a large adenomatoid odontogenic tumour in the mandible, with the involved. This lesion is categorised into three variants of which the more common variant is follicular type which is often mistaken for dentigerous cyst. Adenomatoid odontogenic tumor aot is an uncommon benign odontogenic lesion that affects young patients associated with an impacted tooth, usually canine. Odontogenic tumors are both benign and malignant and have been classified accordingly by who in 1992 which was further divided into sub divisions by white dk in 2004. Adenomatoid odontogenic tumour aot is an uncommon tumour of odontogenic origin, which is usually associated with unerupted teeth or dentigerous cysts, which is usually located in the anterior region of the maxilla without pain, and represents 3% of all odontogenic tumours.
Adenomatoid odontogenic tumor aot is a benign epithelial tumor that shows. There are three subclinical types of this tumour with identical histology. Ameloblastoma, adenomatoid odontogenic tumor, jaws, odontogenic tumors, odontoma how to cite this article. A possible differential diagnosis for the lesion described in this case report is a dentigerous cyst and an adenomatoid odontogenic tumor. International journal of scientific study january 2014 vol 1 issue 4. Odontogenic keratocysts make up around 19% of jaw cysts. Also known as the tumour of the 23rd due to its clinical and radiographic features. Pdf adenomatoid odontogenic tumor the twothirds tumor. Overall, odontogenic tumors are rare and form only a small proportion of the lesions found in the jaw. Adenomatoid odontogenic tumour international journal. Numbers at the top and bottom of the lines indicate cases involving both adjoining regions. Discussion adenomatoid odontogenic tumour is a slowly growing lesion, with a predilection for the anterior maxilla ratio of cases 2. Extrafollicular adenomatoid odontogenic tumour bmj case.
An adenomatoid odontogenic tumour aot is a rare odontogenic tumour that is often misdiagnosed as an odontogenic cyst. Adenomatoid odontogenic tumor aot is a benign tumor, most common in the maxilla, characterized by slow, progressive, painless growth of firm consistency, the size of which usually does not reach large proportions. These expression patterns of matrix proteins agree with the more locally invasive behavior of ameloblastomas in comparison to aots. Dentigerous cyst associated with adenomatoid odontogenic. Abstract adenomatoid odontogenic tumour a relatively rare neoplasm constitutes about 27% of odontogenic cysts and tumours combined. Benign odontogenic tumors are divided into three types based on the presence absense of odontogenic epithelium or ectomesenchyme.
Abstract adenomatoid odontogenic tumor aota benign hamartomatous lesion of odontogenic origin, is an uncommon tumor which affects mainly females in the second decade. Aot is an uncommon lesion of odontogenic origin, which affects young individuals, with a female predilection and mostly occurring in the second decade. Two thirds of cases are located in the anterior maxilla, and one third are present in the. They are also seen more frequently in females, most frequently in the second decade of life. Adenomatoid odontogenic tumor is a hamartomous benign neoplasia of odontogenic origin. A 35year retrospective study of 250 cases in an indian maharashtra teaching institute. Also location is most common in maxillary anterior tooth 1. Adenomatoid odontogenic tumor aot is an uncommon benign tumor of odontogenic origin with a variety of histoarchitectural patterns.
Adenomatoid odontogenic tumor the adenomatoid odontogenic tumor is a benign epithelial odontogenic tumor and it arises from the rests of the dental lamina. The adenomatoid odontogenic tumor is an odontogenic tumor arising from the enamel organ or dental lamina. Abstract adenomatoid odontogenic tumor is the most common tumor between second and third decade of life. Several tumors exist, which only appear to occur in the jaws. It has two clinicopathologic variants, namely intraosseous follicular and extrafollicular and extraosseousperipheral.
Case report cystic adenomatoid odontogenic tumor sonalgrover, 1 ahmedmujibbangalorerahim, 2 nithinkavasseryparakkat, 3 shekharkapoor, 4 kumudmittal, 5 bhushansharma, 1 andanilbangaloreshivappa 6 department of oral pathology and microbiology, christian dental college, cmc, ludhiana, punjab, india. Thus, the aim of this study was to perform a retrospective analysis in a case series of aot, with emphasis on the. Adenomatoid tumors of the scrotum radiology reference. Ameloblastomas and adenomatoid odontogenic tumors aots are common epithelial tumors of odontogenic origin. Adenomatoid odontogenic tumor associated with an impacted. It is slow growing, occurs twice as common in females and usually in the second decade of life.
Adenomatoid odontogenic cyst, adenomatoid odontogenic tumor, hamartoma. Adenomatoid odontogenic tumor involving maxillary sinus a. It is a relatively uncommon neoplasm that accounts for about 3% of all odontogenic tumors being more common in the maxilla and in females, more often associated with. The adenomatoid odontogenic tumour aot is an uncommon, benign lesion of the jaws. When grown, one can palpate a hard and large lesion. Clinical features adenomatoid odontogenic tumors are small, sessile masses on the facial gingiva of the maxilla. Steensland, 1905 it is a hamartomatous, slowly progressive growth that accounts for 2. Adenomatoid odontogenic tumour is a benign hamartomatous, noninvasive lesion with slow but progressive growth. Adenomatoid odontogenic tumor aot is a benign lesion from the dental lamina or its remains. Aot accounts for about 19% of all odontogenic tumours.
Adenomatoid odontogenic tumor, impacted teeth, cone beam computed tomography. The recently revised who classification of odontogenic tumors 3 defines an aot as a tumor composed of odontogenic epithelium in a variety of histoarchitectural patterns, embedded in a mature connective. Further comparisons need to be made with other benign and malignant odontogenic tumors so that unique odontogenic. Adenomatoid odontogenic tumor aot is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst and accounts for about 1% until 9% of all. Adenomatoid odontogenic tumor aot, a benign hamartomatous lesion of odontogenic origin, is an uncommon tumor which affects mainly females in the. Adenomatoid odontogenic tumor aot is a distinct odontogenic tumor that is exclusively odontogenic epithelium in origin which accounts for about 37% of all odontogenic tumors.
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