The papanicolaou society of cytopathology recommendations for pancreatic and biliary cytology. Cancer cytopath 2010 high grade atypical glandular epithelium high. Pitman mb, centeno ba, ali sz, genevay m, stelow e, minokenudson m, fernandezdel castillo c, max schmidt c, brugge w llps of c. A step toward recommendations and guidelines was arranged in collaboration with american society of cytopathology. The papanicolaou society of cytopathology consensus. Overview of origins and subtypes of metastatic tumors in the breast origin subtype number of cases with cyt. Cytopathologic touch preparations imprints from core needle biopsies. Educational curricula for cytomorphology criteria, laboratory methodologies, and quality assurancequality control processes learned over the years from the pap test form a foundation on which the rest of cytopathology expands.
The main purpose of urine cytology is to detect highgrade urothelial carcinoma. Diagnostic terminology and criteria for the cytologic diagnosis of thyroid lesions tarik m. Shidham, md, fiac, frcpath medical college of wisconsin. Is the study of cells structures and their functions. Cervical cytology of the diagnosis atypical squamous cells, cannot exclude high grade squamous intraepithelial lesion. Mary rego, heather smith, brenda sweeney, martha pitman, david wilbur. Is the study of cells structures and their functions a cell is an organized independent mass of protoplasm nucleus and cytoplasm which makes the basic primary structure of an organism. Free cytology books download ebooks online textbooks tutorials. Shidham, md, fiac, frcpath wsu school of medicine, detroit, usa executive editor.
The papanicolaou society of cytopathology system for reporting pancreaticobiliary cytology. Pitman, md clinicians corner the value of urine cytology in the workup of hematuria wassim kassouf, md, cm, frcsc, associate professor, department of urology, mcgill university health center dr. A cell is an organized independent mass of protoplasm nucleus and cytoplasm which. Definitions, criteria, ancillary testing and management will provide the reader with a unified approach to diagnosing and reporting interpretations of cytologic specimens obtained from the pancreaticobiliary tract. Sepe, bhavani moparty, martha bishop pitman, john r. May 2016in the era of personalized medicine 1 it is paramount to collect samples that will have sufficient material not only for an accurate diagnosis but also in many cases for prognostication or eligibility for targeted therapy or both. Grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than positive cytology. This text will serve as a reference guide for pathologists, surgeons, endoscopists and radiologists. The lung was a possible or probable origin in another two cases that table 2. Her focus of research is on current methods of preoperative diagnosis of pancreatic cysts, particularly mucinous cysts of the pancreas. Pitman has written and lectured extensively on the clinical utility of fine needle aspiration biopsy, particularly of the liver and pancreas. Wassim kassouf completed a fellowship in urologic oncology at the university of texas md anderson cancer center in houston. Tissue samples are considered the gold standard in diagnosis. Definitions, criteria and explanatory notes pitman, martha bishop, layfield, lester james on.
Martha bishop pitman, md, department of pathology, massachusetts general hospital, 55 fruit street, boston, ma 01907. Free cytology books download ebooks online textbooks. Cytology specimen management, triage and standardized reporting of fine needle aspiration biopsies of the pancreas the harvard community has made this article openly available. An additional case was diagnosed at autopsy one month after the investigation of the breast lesion. The papanicolaou society of cytopathology has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound eus. Latest guidelines for pancreatobiliary cytologya recap. Martha pitman, md, of massachusetts general hospital, and lester layfield, md, of the university of missouri, spearheaded a nearly threeyear effort to generate guidelines for cytologic diagnosis and recommendations under the auspices of the papanicolaou society of cytopathology, a united states and canadian academy of pathology companion society. The papanicolaou society of cytopathology system for. Hga is most accurately identified in mucinous cyst fluids by. Cytology samples can be easily obtained preoperatively, often without general anaesthesia and sometimes even without sedation, and can be used to screen patients for more comprehensive diagnosis. Richard demay, md university of chicago, chicago, usa martha pitman, md harvard medical school, boston, usa vinod b. Dr martha bishop pitman british association for cytopathology. Guidelines for pancreaticobiliary cytology from the papanicolaou.
Fine needle aspiration cytology is less costly than surgical biopsy in both sample collection and laboratory analysis. Highgrade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than positive cytology. Cytology specimen management, triage and standardized. Guidelines for pancreaticobiliary cytology from the papanicolaou society of cytopathology. Jun 02, 2014 pitman mb, genevay m, yaeger k, chebib i, turner bg, minokenudson m, et al. This text and the terminology developed by the papanicolaou society of cytopathology p. Pitman, md massachusetts general hospital massachusetts general hospital phone.
Shidham, md, fiac, frcpath med college of wi, milwaukee, usa executive editor. Pdf on jun 12, 2014, lester james layfield and others published pancreaticobiliary. View pdf cite save eusguided fna for the diagnosis of gi stromal cell tumors. In certain countries such as the usa, the federal government has mandated a national proficiency testing program for gynecologic cytology. The papanicolaou society of cytopathology system for reporting pancreaticobiliary cytology will provide the reader with a unified approach to diagnosing and reporting cytologic specimens obtained from the pancreaticobiliary tract. The recent advances in pancreas cytology specimen sampling methods have enabled a specific. With this principle in mind, the paris system tps working group, composed of cytopathologists, surgical pathologists, and urologists, has proposed and published a standardized reporting system that includes specific diagnostic categories and cytomorphologic criteria for the reliable diagnosis of highgrade. Standardized terminology and nomenclature for pancreatobiliary. Brugge, md, and mari minokenudson, md cancer cytopathology 2014. Abstract the recent advances in pancreas cytology specimen sampling methods have enabled a specific cytologic diagnosis in most cases.
October 2016 in lecture theatre3 at 5pm at royal free hospital dr. Pitman is the director of the cytopathology laboratory at massachusetts general. The papanicolaou society of cytopathology guidelines. Ali, muriel genevay, ed stelow, md,mari mino kenudson. Pitmans primary research interests are in fine needle aspiration biopsy of the liver and pancreas. The bethesda system for reporting cervical cytology. I do want to brag that this effort was spearheaded by two psc past presidents drs. Cytologic characteristics of circulating epithelioid cells in. Hospital mgh and a professor of pathology at harvard. Pdf the papanicolaou society of cytopathology system for. Pdf on jun 12, 2014, lester james layfield and others published pancreaticobiliary tract cytology.
Your story matters citation yoon, won jae, and martha bishop pitman. Journal of the american society of cytopathology editorial. We want to help promote all of your pathology related books. Brugge, differentiation of pancreatic cysts with optical coherence tomography oct imaging. Department of pathology school of medicine wayne state. Hahn p, eisenberg pj, pitman mb, gazelle gs, mueller pr. One of the most important concept in biology is that a cell is a basic structural and functional unit of living organism. Diagnosing malignancy in bile duct brushings is highly challenging.
We analyzed the utility and relative costeffectiveness of fineneedle aspiration biopsy fnab in the clinical investigation of. Use features like bookmarks, note taking and highlighting while reading the bethesda system for reporting cervical cytology. The papanicolaou society of cytopathology has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound eus guided fineneedle aspiration fna biopsy, techniques of eusfna, terminology and nomenclature of pancreatobiliary disease, ancillary testing and postbiopsy treatment and management. Fna, terminology and nomenclature of pancreatobiliary disease, ancillary testing, and postbiopsy treatment and management. Clinical evaluation, imaging studies, indications for. Role of diagnostic cytology, collection and preparation of material for cytodiagnosis, cytopreparatory techniques of serous effusions, fixation of cytology specimens, staining methods in cytology. The clinical application and cost analysis of fineneedle. Faquin, md phd martha pitman, md fernando schmitt, md, phd, fiac. A followup study with corresponding histology and significance of predicting dysplasia by human papillomavirus dna testing. Manual for cytology pdf 44p this book covers the following topics. The value of cytology in preoperative diagnosis vicente moralesoyarvide md, won jae yoon, md2, thun ingkakul md, david g forcione md, brenna casey, md, william r brugge md, carlos fernandezdel castillo md, and martha b pitman md cancer cytopathology. Nicusor iftimia, sevdenur cizginer, vikram deshpande, martha pitman, servet tatli, nicolaeadrian iftimia, daniel x hammer, mircea mujat, teoman ustun, r. Sarcoidosis is a prevalent disease of unknown cause characterized by granulomatous inflammation that often creates deep andor superficial mass lesions. Pitman s primary research interests are in fine needle aspiration biopsy of the liver and pancreas.
The presence of a pathology report is to convey clinically useful diagnostic information relevant to the findings on the slide that can be used for treatment and management of the patient. Layfield, md2 the newest installment on stateoftheart standards of practice in cytopathology from the papanicolaou society of cytopathology psc focuses on the pancreaticobiliary system. Guidelines for pancreaticobiliary cytology from the. Journey toward bethesda style guidelines from the papanicolaou society of cytopathology. Cytologic predictors of malignancy in bile duct brushings. All 100% were p16 negative on cell block sections of cervical cytology specimen. The papanicolaou society of cytopathology system for reporting. Shidham, md, fiac, frcpath wsu school of medicine, detroit, usa. Definitions, criteria, and explanatory notes kindle edition by nayar, ritu, wilbur, david c download it once and read it on your kindle device, pc, phones or tablets.
Her primary research interests center on the role of cytology in the preoperative diagnosis and management of patients with pancreatic cysts. Hpv testing performed in last 6 months in 7 cases was positive in 3 43% cases. Cytologic characteristics of circulating epithelioid cells. Journal of the american society of cytopathology vol 7. Proper triage and processing of the cytologic specimen is pivotal in making a diagnosis due to the need for ancillary testing in addition to cytological evaluation, which is especially true in the diagnosis of pancreatic cysts. Jun 30, 2017 diagnosing malignancy in bile duct brushings is highly challenging. Cytology sample collection and preparation for veterinary. Cytopathology laboratory massachusetts general hospital. This demands that pathologists and cytotechnologists practicing in the usa undertake yearly testing using. Pitmans phone number, address, hospital affiliations and more. This may involve use of immunohistochemistry, flow cytometry.
Pathologist, massachusetts general hospital subspecialty head and director, cytopathology laboratory professor of pathology, harvard medical school. Recent updates on the role of micrornas in prostate cancer, oudai hassan, aamir ahmad, seema sethi, and fazlul h. Standardized terminology and nomenclature for pancreatobiliary cytology. Richard demay, university of chicago, chicago, usamd martha pitman, md harvard medical school, boston, usa vinod b. Publication date 1921 topics natural sciences, biological sciences in general, general genetics. Clinical evaluation, imaging studies, indications for cytologic study, and preprocedural requirements for duct brushing studies and pancreatic fna. Evaluation of pancreatic lesions that may be interpreted. Pitman is the director of the cytopathology laboratory at massachusetts general hospital mgh and a professor of pathology at harvard medical school hms. Citescore values are based on citation counts in a given year e.
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